Differential Hypoxic Regulation of Hypoxia-Inducible Factors 1α and 2α
نویسندگان
چکیده
منابع مشابه
Mutual antagonism between hypoxia-inducible factors 1α and 2α regulates oxygen sensing and cardio-respiratory homeostasis.
Breathing and blood pressure are under constant homeostatic regulation to maintain optimal oxygen delivery to the tissues. Chemosensory reflexes initiated by the carotid body and catecholamine secretion from the adrenal medulla are the principal mechanisms for maintaining respiratory and cardiovascular homeostasis; however, the underlying molecular mechanisms are not known. Here, we report that...
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ژورنال
عنوان ژورنال: Molecular Cancer Research
سال: 2011
ISSN: 1541-7786,1557-3125
DOI: 10.1158/1541-7786.mcr-11-0053